Do you have a pic or at least more description? What kind of spot? How big? Is it sort of blurry?
What are you water parameters? How long has the tank been set up? What else is in the tank?
Could be an infection of some sort, but you're not giving us much to go on.
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Current setups: 1800 gallon koi pond, 10 gallon planted, 150 gallon reef, other FOWLR tanks
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